If you decide to sleep one night in Pisa, this hotel is modern and great: NH Hotel Cavalieri Pisa. Well placed in the city center, with a very good breakfast buffet. Checked by myself.
To see in Pisa, the Miracles Place with the famous Tower, the river in the city center, and a walk in the Old town, not far from Piazza dei Miracoli.
Eat in Pisa: not near Piazza dei Miracoli, go in Borgo Stretto, Piazza Dante Alighieri, Via San Martino and choose one you like.

Where to sleep in Lucca? I slept in a big hotel near the Train Station, close to the old town outside the wall, there is a useful parking outside. Unfortunately I don’t remember the name, but in the city the choice of accommodation is adeguate: Hotels in Lucca.
Eat in Lucca, go straight here: Cantine Bernardini, Palazzo Bernardini, Via del Suffragio 7.
A place where you should go, definitely, is SAN GIMIGNANO.
Sleep here in the Tuscany countryside: Hotel Vecchio Asilo Via delle Torri, 4 Ulignano, 53030 San Gimignano.
Eat here in San Gimignano: Trattoria Chiribiri Piazza della Madonna 1.
I loved a lot PISTOIA. Slept in Hotel Villa Chiappugi, they have a good restaurant as well.
SIENA as well is unforgettable. I'll soon dedicate a post to this lovely place with all the info I have.
You like the seaside? Drive to VIAREGGIO, and the VERSILIA area.
If you want to have an idea looking pictures, in this page there are some pics about the cities I mentioned: Tuscany pictures.
Buon viaggio in Toscana!!